Metaraminolum [Latin]

Metaraminolum [Latin] Brand names, Metaraminolum [Latin] Analogs

Metaraminolum [Latin] Brand Names Mixture

No information avaliable

Metaraminolum [Latin] Chemical_Formula

C₉H₁₃NO₂

Metaraminolum [Latin] RX_link

http://www.rxlist.com/cgi/generic2/metar.htm

Metaraminolum [Latin] fda sheet

Metaraminolum [Latin] msds (material safety sheet)

Metaraminolum_[Latin] MSDS

Metaraminolum [Latin] Synthesis Reference

Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)

Metaraminolum [Latin] Molecular Weight

167.205 g/mol

Metaraminolum [Latin] Melting Point

107.5 ^oC

Metaraminolum [Latin] H₂O Solubility

1000 g/L

Metaraminolum [Latin] State

Solid

Metaraminolum [Latin] LogP

0.6

Metaraminolum [Latin] Dosage Forms

Intramuscular injection; Intravenous injection

Metaraminolum [Latin] Indication

For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage

Metaraminolum [Latin] Pharmacology

Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

Metaraminolum [Latin] Absorption

The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.

Metaraminolum [Latin] side effects and Toxicity

LD₅₀=240 mg/kg (rat, oral); LD₅₀=99 mg/kg (mouse, oral)

Metaraminolum [Latin] Patient Information

Metaraminolum [Latin] Organisms Affected

Humans and other mammals